Porcilis PCV M Hyo
Active substance
ATC code
Species
Pigs (for fattening).
Indications
For the active immunisation of pigs to reduce viraemia, virus load in lungs and lymphoid tissues, virus shedding caused by porcine circovirus type 2 (PCV2) infection, and severity of lung lesions caused by Mycoplasma hyopneumoniae infection. To reduce the loss of daily weight gain during the finishing period in face of infections with Mycoplasma hyopneumoniae and/or PCV2 (as observed in field studies).
Onset of immunity with single dose vaccination:
PCV2: 2 weeks after vaccination
M. hyopneumoniae: 4 weeks after vaccination.
Onset of immunity with two dose vaccination:
PCV2: 18 days after first vaccination
M. hyopneumoniae: 3 weeks after the second vaccination.
Duration of immunity (both vaccination schedules):
PCV2: 22 weeks after (the last) vaccination
M. hyopneumoniae: 21 weeks after (the last) vaccination.
Dose to be administered and administration route
Before using the vaccine allow it to reach room temperature (15 °C - 25 °C) and shake well before use. Avoid introduction of contamination.
Vaccinate pigs by the intramuscular route in the neck.
Single dose vaccination schedule:
A single dose of 2 ml in pigs starting at 3 weeks of age.
Two-dose vaccination schedule:
Two injections each of 1 ml in pigs starting at 3 days of age with an interval of at least 18 days.
Needle length and diameter should be adapted to the age of the animal.
When PCV2 and/or M. hyopneumoniae infections occur early the two-dose vaccination schedule is recommended.
Mixed use with Porcilis Lawsonia
The Porcilis PCV M Hyo emulsion may be used to reconstitute Porcilis Lawsonia lyophilisate shortly before vaccination in pigs from 3 weeks of age onwards as follows:
Porcilis Lawsonia lyophilisate | Porcilis PCV M Hyo |
50 doses | 100 ml |
100 doses | 200 ml |
For proper reconstitution and correct administration, use the following procedure:
1. Allow Porcilis PCV M Hyo to reach room temperature and shake well before use.
2. Add 5-10 ml Porcilis PCV M Hyo to the Porcilis Lawsonia lyophilisate and mix briefly.
3. Withdraw the reconstituted concentrate from the vial and inject it back into the vial with Porcilis PCV M Hyo. Shake briefly to mix.
4. Use the vaccine mixture within 6 hours of reconstitution. Any vaccine remaining at the end of this time should be discarded.
Dosage:
A single dose (2 ml) of Porcilis Lawsonia mixed with Porcilis PCV M Hyo is given intramuscularly in the neck.
Visual appearance after reconstitution: homogenous white to nearly white emulsion after shaking.
Adverse reactions
Pigs for fattening:
Very common (>1 animal / 10 animals treated): | Elevated temperature1 |
Uncommon (1 to 10 animals / 1 000 animals treated): | Injection site swelling2 Decreased activity3 Lying down3 Uncomfortable3 |
Rare (1 to 10 animals / 10 000 animals treated): | Hypersensitivity reaction4 |
Very rare (<1 animal / 10 000 animals treated, including isolated reports): | Anaphylactic type reaction5 |
1 On the day of vaccination (mean ±1 °C, in individual pigs up to 2 °C). The animals return to normal from 1 to 2 days after the peak temperature is observed.
2 < 2 cm diameter. These reactions disappear within 12 days after the first vaccination of the twodose vaccination schedule and within 3 days after completion of either the single or the two-dose vaccination schedule.
3 Up to one day after vaccination.
4 After the first vaccination of the two-dose vaccination schedule.
5 For the single dose vaccination: May be life threatening. If such reactions occur, appropriate treatment is recommended.
Reporting adverse events is important. It allows continuous safety monitoring of a veterinary medicinal product. Reports should be sent, preferably via a veterinarian, to either the marketing authorisation holder or the national competent authority via the national reporting system. See section ‘Contact details’ of the package leaflet.
