Porcilis PCV
Active substance
ATC code
Species
Pigs
Indications
For the active immunisation of pigs to reduce the virus load in blood and lymphoid tissues and to reduce mortality and weight loss associated with PCV2 infection occurring during the fattening period.
Onset of immunity: 2 weeks
Duration of immunity: 22 weeks.
Dose to be administered and administration route
Before using the vaccine, allow it to reach room temperature and shake well before use. Avoid multiple vial broaching. Use sterile syringes and needles. Avoid introduction of contamination. Avoid use of vaccination equipment with rubber parts.
Vaccination
Administer one dose of 2 ml by intramuscular injection in the neck, in the area behind the ear, according to the following schedule:
In the case of low to medium levels of maternally derived antibodies against PCV2 a single vaccination (2 ml) to pigs from an age of 3 weeks onwards is advised.
When it is expected that higher levels of maternally derived antibodies against PCV2 are present, the following schedule of two vaccinations is advised: the first injection (2 ml) can be given from an age of 3–5 days, the second injection (2 ml) 2–3 weeks later.
High levels of MDA may be expected when sows/gilts are vaccinated against PCV2 virus or when sows/gilts have recently been exposed to high levels of PCV2 virus. In such cases it is advised to perform PCV2 serology, using suitable diagnostics, to select the most appropriate vaccination schedule. In case of doubt, apply the two shot vaccination schedule.
Adverse reactions
In laboratory studies and field trials:
Transient local reactions at the injection site were very commonly observed after vaccination mainly in the form of a hard, warm and sometimes painful swelling (diameter up to 10 cm). These reactions resolve spontaneously over a period of approximately 14–21 days without any major consequence on the general health status of the animals. Immediate systemic hypersensitivity-like reactions were commonly observed after vaccination, resulting in minor neurological symptoms such as tremors and/or excitation, which normally resolve within minutes without requiring treatment. A transient increase in body temperature, normally not exceeding 1 °C, was very commonly observed until 2 days after vaccination. In individual animals, an increase of rectal temperature of 2.5 °C lasting less than 24 hours was uncommonly observed.
In some piglets depression and a reduced feed intake for up to 5 days were uncommonly observed. Vaccination may result in a transient impairment of growth rate in the immediate period after administration of the vaccine.
In post marketing experience:
In very rare cases anaphylactic-type reactions can occur, which may be lifethreatening. In the event of such reactions, treatment may be needed.
The frequency of adverse reactions is defined using the following convention:
- very common (more than 1 in 10 animals treated displaying adverse reactions)
- common (more than 1 but less than 10 animals in 100 animals treated)
- uncommon (more than 1 but less than 10 animals in 1,000 animals treated)
- rare (more than 1 but less than 10 animals in 10,000 animals treated)
- very rare (less than 1 animal in 10,000 animals, including isolated reports treated).
