Finadyne vet.
Active substance
ATC code
Species
Cattle, horses and pigs.
Indications
In Cattle:
For the control of acute inflammation associated with respiratory disease.
Finadyne has also been shown to have some benefit in the treatment of experimental acute bovine pulmonary emphysema (Fog Fever).
Finadyne Solution may be used as adjunctive therapy in the treatment of acute mastitis.
In Horses:
For the alleviation of inflammation and pain associated with musculo-skeletal disorders.
For the alleviation of visceral pain associated with colic in the horse.
In Pigs:
For use as an adjunctive therapy in the treatment of swine respiratory diseases.
Dose to be administered and administration route
Cattle
2 ml per 45 kg bodyweight (equivalent to 2.2 mg flunixin per kg) administered intravenously. Repeat as necessary at 24 hour intervals for up to 5 consecutive days.
Horses
By intravenous injection for musculo-skeletal disorders at the following rate: 1 ml per 45 kg bodyweight (1.1 mg flunixin/kg) once daily for up to 5 days according to clinical response.
By intravenous injection for colic at the following rate:
1 ml per 45 kg bodyweight (1.1 mg flunixin/kg) repeated once or twice if colic recurs.
For the treatment of endotoxaemia or septic shock associated with gastric torsion and with other conditions in which the circulation of blood to the gastro-intestinal tract is compromised: 0.25 mg/kg every 6-8 hours, by intravenous injection.
Pigs
2 ml per 45 kg bodyweight (equivalent to 2.2 mg flunixin/kg) once by intramuscular injection, in the neck, in conjunction with appropriate antimicrobial therapy. The injection volume should be limited to a maximum of 5 ml per injection site.
An appropriately graduated syringe must be used to allow accurate administration of the required dose volume. This is particularly important when injecting small volumes.
When intramuscular injection is used, the dose should be divided between two injection sites on either side of the neck.
In order to prevent excessive broaching of the rubber stopper, it is not recommended that the stopper is broached more than 25 times.
Adverse reactions
Flunixin meglumine is a non-steroidal anti-inflammatory drug (NSAID). Untoward effects include gastro-intestinal irritation, ulceration and, in dehydrated or hypovolaemic animals, potential for renal damage.
In pigs transient irritation may occur at the injection site, this resolves spontaneously within 14 days.
Anaphylactic-type reactions have been reported in horses and cattle, resulting in collapse following intravenous injection. Such reactions, on very rare occasions have been life-threatening in spontaneous pharmacovigilance reports.
The frequency of adverse reactions is defined using the following convention:
- very common (more than 1 in 10 animals treated displaying adverse reaction(s))
- common (more than 1 but less than 10 animals in 100 animals treated)
- uncommon (more than 1 but less than 10 animals in 1,000 animals treated)
- rare (more than 1 but less than 10 animals in 10,000 animals treated)
- very rare (less than 1 animal in 10,000 animals treated, including isolated reports).