Nobilis Salenvac T
Active substance
ATC code
Species
Chickens (breeders and layers)
Indications
For the active immunisation of chickens and the passive immunisation of the progeny to reduce caecum colonisation and faecal excretion with S. Enteritidis and S. Typhimurium.
Active immunity:
Onset of immunity: 4 weeks after the second administration
Duration of immunity: until approximately 56-60 weeks of age for chickens vaccinated at 12 and 16 weeks.
Minor indication: In exceptional circumstances chickens from one day of age may be vaccinated in order to protect them in an environment where they are likely to become infected at an early stage in the rearing phase (epidemiologically indicated by recent outbreak of Salmonella or high infection pressure on the site).
Onset of immunity: 4 weeks after the second administration.
Passive immunity:
Onset of immunity: day one after hatching.
Duration of immunity: until 14 days after hatching.
Passive immunity is transferred from 4 weeks after the second vaccination up to 59 weeks of age of the parent bird.
Dose to be administered and administration route
Standard vaccination:
Intramuscular injection of one dose of 0.5 ml.
For active immunisation of layers and breeders:
Two vaccinations, with an interval of four weeks should be given.
The recommended age for vaccination is 12 and 16 weeks of age.
Emergency vaccination (when epidemiologically indicated in high-risk environments):
Intramuscular injection of one dose of 0.1 ml in one-day-old chicks.
After an interval of 4 weeks a repeat vaccination with a dose of 0.5 ml should be given.
For passive immunisation of progeny of breeders:
Two vaccinations, with an interval of at least four weeks should be given. The recommended age for first vaccination is at 6-12 weeks of age and for the second vaccination at 13-16 weeks of age.
In case the induction of active- and passive immunity is intended in breeders and their offspring, the vaccination scheme for active immunisation should be followed.
Hygiene measures and good husbandry practices should also play an important part of a control programme to reduce the incidence of Salmonella infection.
Adverse reactions
The vaccine contains an adjuvant and vaccination may result in temporary swellings at the injection site.
In chickens of 4 weeks of age and above (receiving a dose of 0.5 ml), vaccination may rarely result in transient small palpable nodules at the injection site (reaching a maximum size of 1 cm2), evident immediately after vaccination and generally lasting only 1-2 days. Vaccination may also be associated with transient dullness, lethargy and lameness, lasting up to 2 days.
In one-day-old chicks (receiving 0.1 ml) the reactions are more noticeable.
It should be taken into account that post-vaccination injection site swellings are generally more evident than when administering 0.5 ml to birds of 4 weeks of age or older, and occasionally, the whole thigh may become swollen. These reactions are temporary and in the majority of cases resolved within 7 days.
Exceptionally, a swelling may still be detectable 15 days after inoculation. In addition, after vaccination a significant proportion of the birds may show signs of lethargy, dullness and lameness, and a reduction of weight gain.
