Nobilis Reo inac
ATC code
Species
Chickens (breeding birds).
Indications
For the active immunisation of parent birds for the passive immunisation of their progeny, to reduce mortality and clinical signs of disease caused by avian reoviruses.
Active immunity develops in the parent within 4 weeks, and offspring born at any stage of the subsequent laying period will have passive immunity against reovirus infections for protection during the susceptible period in the early phase of life.
Dose to be administered and administration route
Intramuscular or subcutaneous use.
The vaccine Nobilis REO inac should be given to birds around 10–20 weeks of age but not later than 4 weeks before the expected onset of lay.
Dose: 0.5 ml vaccine per bird via intramuscular injection in the thigh or chest muscle or by subcutaneous injection into the back of the neck, using a medium sized needle (20g x ½”). For an optimal response in birds not primed by field virus, two vaccinations should be given approximately 6 weeks apart.
Allow the vaccine to reach ambient temperature (15 °C – 25 °C) before use.
The vaccine may occasionally separate into two layers on storage. This in no way affects its potency, but the vaccine should be shaken vigorously before and during use to ensure a good emulsification.
An automatic injection system, incorporating a means to prevent back flushing and hence possible contamination of the vaccine, should be used to administer the vaccine.
Ensure that vaccination equipment is clean and sterile before use. Do not use vaccination equipment with rubber parts as the excipient may damage certain types of rubber.
Adverse reactions
It is very common that a slight transient swelling (resolved within 3 weeks) may be felt in 50% of the vaccinated birds at the site of vaccination.
The frequency of adverse reactions is defined using the following convention:
- very common (more than 1 in 10 animals displaying adverse reactions during the course of one treatment)
- common (more than 1 but less than 10 animals in 100 animals)
- uncommon (more than 1 but less than 10 animals in 1,000 animals)
- rare (more than 1 but less than 10 animals in 10,000 animals)
- very rare (less than 1 animal in 10,000 animals, including isolated reports).
