Oxytocin-S
Active substance
ATC code
Species
Cattle, horses, pigs, sheep, goats, cats and dogs
Indications
Injections with this product will initiate strong, regular and purposeful contractions of the uterine muscle especially in the later stages of pregnancy and post-partum. It also evokes the 'let-down' of milk although it has no action on the smooth muscles of the gut or urinary bladder, nor is it effective in the treatment of diabetes insipidus. The absence of vasopressor and antidiuretic effects make it particularly suitable for obstetric use (stimulation of parturition, promotion of uterine involution and control of post-partum haemorrhage) and the treatment of agalactia.
The product is indicated for:
- stimulation of uterine contraction to facilitate parturition in the presence of a fully dilated cervix
- to promote involution of the post-parturient uterus and thus aid the passage of retained placenta
- to aid in control of post-partum haemorrhage
- promotion of milk 'let-down' in cases of agalactia and to facilitate ‘stripping out’ of infected quarters in the treatment of mastitis in cows.
Dose to be administered and administration route
The product should normally be given by deep intramuscular injection.
|
Species |
Dosage |
mls |
|
Queen |
2-5 iu |
0.2-0.5 ml |
|
Bitch |
2-10 iu |
0.2-1.0 ml |
|
Ewe, goat, sow |
2-10 iu |
0.2-1.0 ml |
|
Mare |
10-40 iu |
1.0-4.0 ml |
|
Cow Indications other than mastitis as listed in section 4. For mastitis treatment see below. |
10-40 iu |
1.0-4.0 ml |
Adjunct to mastitis treatment in cows:
A single dose of up to 80 iu (8 ml) prior to stripping out before first mastitis treatment followed by repeated doses of 20 iu (2 ml) prior to each stripping out 2 or 3 times daily while mastitis treatment continues.
Where the intravenous route is used, these doses should be reduced to onequarter of the intramuscular dose and the injection given slowly at a dilution of 1 in 10 Water for Injections Ph.Eur. Where speed of onset is not a priority, the product may be given by the subcutaneous route.
A low initial dosage is recommended by any route as repeat administration is permissible.
Large doses may be employed in post-parturient animals.
Adverse reactions
None known
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