Thiamazole
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Thiamazole is used to treat hyperthyroidism in animals. It reduces thyroid hormone production and is primarily used in cats but may also be applied to other species at the veterinarian's discretion.
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Thiamazole is used to treat hyperthyroidism in animals. It reduces thyroid hormone production and is primarily used in cats but may also be applied to other species at the veterinarian's discretion.
Essential insights
- Inhibition of thyroid hormone synthesis: Thiamazole works by inhibiting the enzyme thyroid peroxidase, essential for the production of thyroxine (T4) and triiodothyronine (T3).
- Reduction of iodine incorporation: Thiamazole prevents the incorporation of iodine into thyroglobulin, a necessary step in thyroid hormone formation.
- Slow clinical effect: While the substance quickly inhibits hormone synthesis, it takes time to reduce circulating hormone levels and alleviate hyperthyroidism symptoms.
- Selective Toxicity: Thiamazole specifically targets thyroid tissue without affecting other endocrine functions, making it relatively safe for animals when used appropriately.
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