Potassium bromide
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Potassium bromide is an anticonvulsant used to treat epilepsy in animals. It is commonly prescribed for long-term management in dogs and occasionally in cats. Potassium bromide is used as monotherapy or in combination with other anticonvulsants, such as phenobarbital, to control seizures and reduce the frequency of epileptic episodes.
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Potassium bromide is an anticonvulsant used to treat epilepsy in animals. It is commonly prescribed for long-term management in dogs and occasionally in cats. Potassium bromide is used as monotherapy or in combination with other anticonvulsants, such as phenobarbital, to control seizures and reduce the frequency of epileptic episodes.
Essential insights
- Neuron Hyperpolarization:
Potassium bromide works by increasing the movement of bromide ions across cell membranes. These bromide ions replace chloride ions in nerve cells, leading to hyperpolarization and reduced neuronal excitability. - Long Half-Life:
The substance has a long half-life, ensuring steady blood concentrations, but it may take weeks to achieve full efficacy. - Potassium bromide is generally well-tolerated but may cause side effects such as sedation, ataxia, and, in rare cases, gastrointestinal symptoms. Careful dose adjustments are crucial to minimize the risk of toxicity.
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