Clenbuterol

Clenbuterol is a β2-adrenergic agonist used primarily for its bronchodilator effects, especially in treating respiratory conditions in horses. It is also sometimes used for its anabolic properties. Read more

Clenbuterol is a β2-adrenergic agonist used primarily for its bronchodilator effects, especially in treating respiratory conditions in horses. It is also sometimes used for its anabolic properties.

Essential insights

• β2-Adrenergic Receptor Stimulation: Clenbuterol selectively stimulates β2-adrenergic receptors, which are primarily found in the smooth muscle of the airways. This stimulation leads to relaxation of these muscles, resulting in bronchodilation and improved airflow.
• Bronchodilation: By activating β2-receptors, clenbuterol causes the smooth muscles of the bronchial tubes to relax, reducing airway constriction and easing breathing. This makes it effective in managing conditions such as asthma or chronic obstructive pulmonary disease (COPD) in horses.
• Anabolic Effects: Clenbuterol has been used for its anabolic (muscle-building) effects, promoting muscle growth and reducing fat deposition. This application is more controversial and less common due to potential abuse and regulatory concerns.
• Stimulation of Metabolic Rate: Clenbuterol can also increase the metabolic rate and promote lipolysis, which can contribute to weight loss or changes in body composition.
• Its use is regulated due to potential side effects, including cardiac issues and muscle tremors, and it is banned or restricted in many competitive animal sports due to concerns about unfair advantage and substance residues.