Oncept IL-2
Active substance
ATC code
Species
Cats.
Indications
Immunotherapy to be used in addition to surgery and radiotherapy in cats with fibrosarcoma (2-5 cm diameter) without metastasis or lymph node involvement in order to reduce the risk of relapse and to increase the time to relapse (local recurrence or metastasis). This was demonstrated in a field trial over a period of 2 years.
Dose to be administered and administration route
Subcutaneous use.
After reconstitution of the lyophilisate with the solvent, shake gently and administer five injections (each approximately 0.2 ml) around the tumour excision site: one injection at each corner and one injection at the centre of a 5 cm x 5 cm square centred on the middle of the surgical scar.
Treatment course: 4 administrations at 1-week intervals (day 0, day 7, day 14, day 21) followed by 2 administrations at 2-week intervals (day 35, day 49).
Start the treatment course the day before radiation therapy, preferably within one month after surgical excision.
Adverse reactions
A moderate local reaction (pain on palpation, swelling, scratching) occurred very commonly in safety studies. It usually disappeared spontaneously within 1 week at most.
Transient apathy and hyperthermia (above 39.5 °C) occurred commonly in field studies.
The frequency of adverse reactions is defined using the following convention:
- very common (more than 1 in 10 animals treated displaying adverse reaction(s))
- common (more than 1 but less than 10 animals in 100 animals treated)
- uncommon (more than 1 but less than 10 animals in 1,000 animals treated)
- rare (more than 1 but less than 10 animals in 10,000 animals treated)
- very rare (less than 1 animal in 10,000 animals treated, including isolated reports).
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| Art. Nr. | 04491/5039 |
| EAN | 3661103040583 |
