Chanazone
Active substance
ATC code
Species
Horses (non-food producing horses).
Indications
The product is indicated for the treatment of musculoskeletal conditions in the horse where relief from pain and a reduction in the associated inflammation is required, e.g. in lameness associated with osteoarthritic conditions, bursitis, laminitis and soft tissue inflammation, particularly where continued mobility is considered desirable.
It is also of value in limiting post surgical inflammation, myositis and other soft tissue inflammation.
Phenylbutazone powder can be used as an anti-pyretic where this is considered advisable e.g. in viral respiratory infections.
Dose to be administered and administration route
Oral use.
The recommended dose rate is 4.4 – 8.8 mg/kg per day.
For each 450 kg bodyweight the following dosage guide should be used according to individual response:
Day 1 4.4 mg phenylbutazone/kg of bodyweight twice daily, (equivalent to two sachets or 10 g of the product twice daily).
Day 2-4 2.2 mg phenylbutazone /kg of bodyweight twice daily, (equivalent to one sachet or 5 g of the product twice daily) followed by 2.2 mg phenylbutazone /kg of bodyweight daily, (equivalent to one sachet or 5 g of the product daily) or on alternate days as required.
If no response is evident after 4-5 days, discontinue treatment. Hay may delay the absorption of phenylbutazone and so the onset of a clinical effect. It is advisable not to administer hay immediately prior to, or during the administration of the product.
For ease of administration the product may be mixed with a quantity of bran or oats before each treatment.
Adverse reactions
In common with other NSAIDs that inhibit prostaglandin synthesis, there may be gastric and/or renal intolerance. This is usually associated with overdosage and such events are rare (more than 1 but less than 10 animals in 10,000 animals treated). Recovery is usual on cessation of treatment and following the initiation of supportive symptomatic therapy (see 4.10 for further information).
Blood dyscrasia may occur.
Ponies are very sensitive to gastric ulceration with this product, even at therapeutic doses (diarrhoea, ulceration in the mouth and hypoproteinaemia may also be seen).
If adverse reactions occur, treatment should be discontinued and the advice of a veterinarian should be sought.
Dispensing
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