Frontline Combo vet. (> 40 kg)
ATC code
Species
Dogs (weighing over 40 kg bw).
Indications
To be used against infestations with fleas, alone or in association with ticks and/or biting lice.
- Treatment of flea infestations (Ctenocephalides spp.). Insecticidal efficacy against new infestations with adult fleas persists for 8 weeks. Prevention of the multiplication of fleas by inhibiting of the development of eggs (ovicidal activity) and larvae and pupae (larvicidal activity) originating from eggs laid by adult fleas for eight weeks after application.
- Treatment of tick infestations (Ixodes ricinus, Dermacentor variabilis, Dermacentor reticulatus, Rhipicephalus sanguineus). The veterinary medicinal product has a persistent acaricidal efficacy for up to 4 weeks against ticks.
- Treatment of infestations with biting lice (Trichodectes canis).
The veterinary medicinal product can be used as part of a treatment strategy for the control of Flea Allergy Dermatitis (FAD).
Dose to be administered and administration route
Spot-on use.
The minimum dose is 6.7 mg/kg bw of fipronil and 6 mg/kg bw of (S)-methoprene, corresponding to one pipette of 4.02 ml (XL) per dog (weighing over 40 kg). To ensure a correct dosage, body weight should be determined as accurately as possible. Underdosing could result in ineffective use and may favour resistance development.
For infestations with fleas and/or ticks, the need for and frequency of retreatment(s)should be based on professional advice and should take into account the local epidemiological situation and the animal’s lifestyle. In the absence of safety studies, the minimum treatment interval is 4 weeks.
Method of administration:
Hold the pipette upright. Tap the narrow part of the pipette to ensure the contents remain within the main body of the pipette. Snap back the tip. Part the coat on the back of the animal at the base of the neck in front of the shoulder blades until the skin is visible. Place the tip of the pipette on the skin and squeeze the pipette several times to empty its contents completely and directly onto the skin in one spot. Temporary changes to the coat (clumped/greasy hair) may be noted at the application site.
Adverse reactions
Dogs:
Very rare (<1 animal / 10,000 animals treated, including isolated reports): |
Application site reactions (skin discoloration1, hair loss1, itching1, reddening1). Generalised itching or hair loss. Hypersalivation2, vomiting, respiratory signs. Increased sensitivity to stimulation3, depression3, other nervous signs3. |
1Transient.
2If licking occurs, a brief period of hypersalivation may be observed due mainly to the nature of the carrier.
3Reversible.
Reporting adverse events is important. It allows continuous safety monitoring of a veterinary medicinal product. Reports should be sent, preferably via a veterinarian, to either the marketing authorisation holder or its local representative or the national competent authority via the national reporting system. See the package leaflet for respective contact details.
Dispensing
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Art. Nr. | 08327/5016 |
EAN | 3661103006305 |