Rispoval RS + PI3 IntraNasal
Active substance
ATC code
Species
Cattle
Indications
For active immunisation of maternally derived antibody positive or negative calves from 9 days of age against BRSV and PI3V, to reduce the mean titre and duration of excretion of both viruses.
Onset of protective immunity: 5 days for BRSV and 10 days for PI3V after a single vaccination.
Duration of protective immunity: 12 weeks following a single dose. The duration of protective immunity against the PI3V fraction may be reduced in MDA positive calves vaccinated before 3 weeks of age.
Dose to be administered and administration route
Reconstitute the 1 dose and 5 dose presentations by aseptically adding all the liquid to the vial containing the powder components. Shake well before use.
Reconstitute the 25 dose presentation by mixing the lyophilised fraction with the solvent in 2 steps:
1. Inject 10 ml of the liquid fraction on the lyophilised plug in the freeze dried vial.
2. Shake well and extract the reconstituted lyophilised fraction from the freeze dried vial and mix with the liquid fraction in the liquid fraction vial.
Shake well before use.
Vaccination programme:
A single dose of 2 ml of reconstituted vaccine should be given intranasally using the intranasal applicators provided to cattle from the age of 9 days. It is recommended to change applicators between animals to avoid transmitting infectious organisms.
Adverse reactions
Published evidence shows that on rare occasions repeated exposure to RSV may trigger hypersensitivity reactions. In colostrum-deprived animals vaccinated before 3 weeks of age with a 10x overdose of vaccine, transient temperature increase, nutritional scour, abnormal faeces and demeanour were observed.
