Poulvac MD Vac
Active substance
ATC code
Species
Chickens.
Indications
To prevent mortality and clinical signs due to infection with Marek's disease virus. Onset of immunity has been demonstrated from 5 days after vaccination. No information is available on the duration of the protection elicited by vaccination. However, experience in the field suggests that Marek’s disease vaccine virus strains and antibody titres persist for up to 2 years after vaccination.
Dose to be administered and administration route
One dose of 0.2 ml per chicken.
The vaccine is to be administered either by intramuscular injection in the thigh or by subcutaneous injection in the neck to one-day-old chickens.
Reconstitute each 1,000 doses of Poulvac MD-Vac with 200 ml of diluent at room temperature. Remove the centre tabs of aluminium seals on both vaccine vial and diluent bottle, leaving intact the outer ring on both vial and bottle. Cleanse rubber stoppers with alcohol and allow to dry. All equipment used for vaccination should be sterile and contain no traces of detergents or disinfectants. Using a sterile needle and syringe, insert through diluent bottle stopper and withdraw 3 ml of diluent. Transfer by inserting through vaccine vial stopper. After slight agitation of the vial to ensure that the vaccine has dissolved, insert needle and withdraw entire contents into the syringe. Remove the syringe containing all the reconstituted vaccine from vial and re-insert into diluent bottle. Expel syringe contents into diluent. The reconstituted vaccine is now ready for use. For administration of the vaccine an automatic syringe with a 23 gauge x 1 inch (0.60 x 25 mm) needle is recommended. Inject each chick intramuscularly with 0.2 ml of vaccine, the usual site being the upper thigh, or subcutaneously in the neck.
Use within 2 hours of reconstitution.
Adverse reactions
No local or systemic reactions have been observed following the administration of the vaccine during safety studies. However, and in common with other immunological products, it is expected that local or systemic reactions may occur in a very small proportion of vaccinated birds.
