Tranquinervin vet.
Active substance
ATC code
Species
Horses.
Indications
Anaesthetic Premedication: Following acepromazine administration, the amount of anaesthetic necessary to induce anaesthesia is considerably reduced.
Tranquilisation: Acepromazine tranquilisation (ataraxy) involves a modification of temperament which is not associated with hypnosis, narcosis or marked sedation. This is achieved with low doses of acepromazine. At low doses, acepromazine reduces anxiety which is beneficial for use in horses prior to shoeing or transportation.
Sedation: At higher dose rates acepromazine is an effective sedative, as an adjunct to, or replacement for, physical restraint e.g. dentistry, handling and shoeing. The relaxant effects aid examination of the penis in horses and the treatment of tetanus and choke.
Dose to be administered and administration route
For intramuscular or intravenous injection. In case of intravenous injection, it is recommended the injection is made slowly.
0.03−0.10 mg acepromazine per kg bodyweight, equivalent to 0.15−0.5 ml product per 50 kg bodyweight.
Normally, single doses of acepromazine are administered. Long term use is not recommended. On the rare occasions that repeat dosing is required, the dosing interval should be 36−48 hours.
Take adequate precautions to maintain sterility. Avoid the introduction of contamination during use. Should any apparent growth or discolouration occur, discard the product. The maximum number of vial punctures when using needle sizes of 21G and 23G should not exceed 100 and when using a 18G needle, the maximum should not exceed 40.
Adverse reactions
Acepromazine may cause hypotension (common) and lowered haematocrit (very common). Reversible paralysis of the retractor penis muscle has been associated with the use of parenterally administered acepromazine in horses (very common). Acepromazine has caused paraphimosis (uncommon), sometimes as a sequel to priapism, however this only very rarely results in permanent penile dysfunction. When extrusion of the penis occurs, the owner should be advised to inform his veterinary surgeon if retraction of the penis does not take place within 2−3 hours. Suitable treatments have been described in the veterinary literature e.g. manual compression during the period of general anaesthesia, penile support and manual compression, use of an Esmarch bandage, or drug reversal (e.g. slow intravenous administration of benztropine mesylate).
Accidental intracarotid injection in horses can produce clinical signs ranging from disorientation to convulsive seizures and death.
The frequency of adverse reactions is defined using the following convention:
- very common (more than 1 in 10 animals treated displaying adverse reactions(s))
- common (more than 1 but less than 10 animals in 100 animals treated)
- uncommon (more than 1 but less than 10 animals in 1,000 animals treated)
- rare (more than 1 but less than 10 animals is 10,000 animals treated)
- very rare (less than 1 animal in 10,000 animals treated, including isolated reports)
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| Art. Nr. | |
| EAN | 8718469443956 |
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