Daxocox
Active substance
ATC code
Species
Dogs
Indications
For the treatment of pain and inflammation associated with osteoarthritis (or degenerative joint disease) in dogs.
Dose to be administered and administration route
Oral use.
Dosing interval is ONCE PER WEEK.
First dose: 8 mg enflicoxib per kg body weight.
Maintenance dose: repeat the treatment every 7 days at the dose of 4 mg enflicoxib per kg body weight.
The veterinary medicinal product should be given immediately before or with the dog’s meal. The bodyweight of animals to be treated should be accurately determined to ensure administration of the correct dose.
Number of tablets to be administered
|
FIRST DOSE 8 mg/kg |
MAINTENANCE DOSE 4 mg/kg |
|||||||||
| Body weight (Kg) /Tablet size (mg) |
15 mg |
30 mg |
45 mg |
70 mg |
100 mg |
15 mg |
30 mg |
45 mg |
70 mg |
100 mg |
| 3 - 4.9 | 2 | 1 | ||||||||
| 5 - 7.5 | 2 | 1 | ||||||||
| 7.6 - 11.2 | 2 | 1 | ||||||||
| 11.3 - 15 | 4 | 2 | ||||||||
| 15.1 - 17.5 | 2 | 1 | ||||||||
| 17.6 - 25 | 2 | 1 | ||||||||
| 25.1 - 35 | 4 | 2 | ||||||||
| 35.1 - 50 | 4 | 2 | ||||||||
| 50.1 - 75 | 6 | 3 | ||||||||
Adverse reactions
Vomiting, soft faeces and/or diarrhoea have been commonly reported in clinical trials, but most cases recovered without treatment.
Apathy, loss of appetite or haemorrhagic diarrhoea have been reported in uncommon cases.
Gastrointestinal ulceration has been reported in uncommon cases.
Elevated blood urea and serum cholesterol levels were observed in healthy, young dogs at the recommended dose in a laboratory safety study.
In case of adverse reactions the use of the veterinary medicinal product should be stopped and general supportive therapy, as for clinical overdose with NSAIDs, should be applied until complete resolution of the signs. Particular attention should be paid to maintain haemodynamic status.
Gastrointestinal protectants and parenteral fluids, as appropriate, may be required for animals that experience gastrointestinal or renal adverse reactions.
The frequency of adverse reactions is defined using the following convention:
- very common (more than 1 in 10 animals treated displaying adverse reaction(s))
- common (more than 1 but less than 10 animals in 100 animals treated)
- uncommon (more than 1 but less than 10 animals in 1,000 animals treated)
- rare (more than 1 but less than 10 animals in 10,000 animals treated)
- very rare (less than 1 animal in 10,000 animals treated, including isolated reports).
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| Art. Nr. | 32742/5003 |
| EAN | 5055037402940 |
