Zorabel

Administration: In drinking water use

The recommended dose rate is 7 mg toltrazuril per kg of body weight (equivalent to 28 ml of medicinal product per 100 kg of body weight) daily given for 2 consecutive days.

In order to ensure administration of a correct dose, accurately determine the body weight of the animals.

The treatment is recommended to be given either continuously over 24 h or alternatively at a treatment duration of 8 hours per day.

For the preparation of medicated water the body weight of the animals to be treated and their actual daily water consumption should be taken into account. Consumption may vary depending on factors like species, age, state of health, breed and husbandry system (e.g. different temperature, different light regimes).

Considering continuous treatment over 24 hours the following calculation should be made for providing the required amount of veterinary medicinal product in ml per litre drinking water:

Total demand of ZORABEL 25 mg/ml per day (24 hours):

The calculated volume (x ml ZORABEL 25 mg/ml per litre) should then be multiplied with the total daily water consumption (l) for the 24 hour period.

Considering a treatment duration of 8 hours per day the following calculation should be made for providing the required amount of veterinary medicinal product in ml per litre drinking water:

Total demand of ZORABEL 25 mg/ml for a treatment duration of 8 hours:

The calculated volume (x ml ZORABEL 25 mg/ml per litre) should then be multiplied with the water consumption (l) for the 8 hour period.

The veterinary medicinal product should be dissolved in drinking water (gentle mixing) before use.

The use of acidic water may cause precipitation of the active substance at recommended doses. The solution should be prepared daily.

At doses ranging from 1 ml to 3 ml of the veterinary medicinal product per litre of drinking water, the solubility is ensured over the treatment period. Dilutions more concentrated than 3:1,000 (3 ml of product to 1 litre drinking water) may result in precipitation.

Because of potential solubility issue, the administration via header tanks should be avoided.

The use of suitably calibrated weighing equipment is recommended if part of containers is used.

Sufficient access to the system of water supply should be available for the animals to be treated to ensure adequate water consumption. No other source of drinking water should be available during the medication period. In free range husbandry systems animals should be kept in the stable during treatment.

After the end of the medication period the water supply system should be cleaned appropriately to avoid intake of sub-therapeutic amounts of the active substance.