Entericolix
Active substance
ATC code
Species
Pigs (sows and gilts for reproduction).
Indications
Vaccination of sows and gilts for the passive immunization of piglets against colibacillosis caused by enteropathogenic and enterotoxigenic E. coli strains expressing F4ac, F5, F6, F18ac and F41 adhesins, against oedema disease caused by E. coli strain expressing F18ab adhesin and against necrotic enteritis caused by C. perfringens type C.
Neonatal piglets
- The vaccine reduces mortality and clinical signs (severe diarrhoea) due to colibacillosis.
- The vaccine reduces mortality and clinical signs due to necrotic enteritis caused by C. perfringens type C.
Weaned piglets
- The vaccine reduces mortality and clinical signs due to oedema disease
- The vaccine reduces clinical signs (severe diarrhoea) of colibacillosis
- The vaccine reduces clinical signs of chronic enteritis due to C.
perfringens type C
Duration of immunity:
- 21 days for infections caused by F4ac, F18ac, (colibacillosis) and Clostridium perfringens type C (necrotic enteritis)
- 21 days for antibodies against F5, F6 and F41, however the protective efficacy of the antibody levels was not established
- 28 days for infections caused by F18ab (oedema disease)
Dose to be administered and administration route
Intramuscular use.
Shake vigorously before use and at intervals during use.
Avoid introduction of contamination during use.
Doses
Sows and gilts: 2 ml.
Before use, allow the vaccine to reach room temperature and shake the bottle vigorously. Inoculate the corresponding dose by deep intramuscular injection in the neck muscles. It is very important to use needles of appropriate length according to the weight of the animal.
It is recommended that the second dose should be given preferably on the alternate side.
Vaccination schedule
Pregnant sows: The initial course consists of two doses. Administer one dose 7 weeks before farrowing followed by a second dose 4 weeks before farrowing.
Revaccinate with a single dose 4 weeks before farrowing in subsequent gestation periods.
Adverse reactions
A transient increase in body temperature (maximum 2ºC) can be observed between 4–24 hours after vaccination, this event is very common. Temperatures return to normal values within 24–48 hours.
The vaccine can produce short term apathy between 1 and 2 days postvaccination, this event is common. Apathy may last for up to 7 days after vaccination, however this event is uncommon.
Injection site reactions (swelling and reddening) occurred rarely, with a maximum of 3 cm of diameter and a maximum of 10 days of duration.
Anaphylactic reactions (which may be fatal) have been reported very rarely
The frequency of adverse reactions is defined using the following convention:
- very common (more than 1 in 10 animals treated displaying adverse reaction(s))
- common (more than 1 but less than 10 animals in 100 animals treated)
- uncommon (more than 1 but less than 10 animals in 1,000 animals treated)
- rare (more than 1 but less than 10 animals in 10,000 animals treated)
- very rare (less than 1 animal in 10,000 animals treated, including isolated reports).
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| Art. Nr. | 30824/4003 |
| EAN | 5012917040050 |
