Mhyosphere PCV ID
Active substance
ATC code
Species
Pigs.
Indications
For the active immunisation of pigs:
- to reduce lung lesions associated with porcine enzootic pneumonia caused by Mycoplasma hyopneumoniae. Also, to reduce the incidence of these lesions (as observed in field studies).
- to reduce viraemia, virus load in lungs and lymphoid tissues and the duration of the viraemic period associated with diseases caused by Porcine circovirus type 2 (PCV2). Efficacy against PCV2 genotypes a, b and d has been demonstrated in field studies.
- to reduce culling rate and the loss of daily weight gain caused by Mycoplasma hyopneumoniae and/or PCV2 related diseases (as observed at 6 months of age in field studies).
Mycoplasma hyopneumoniae:
Onset of immunity: 3 weeks after vaccination.
Duration of immunity: 23 weeks after vaccination.
Porcine circovirus type 2:
Onset of immunity: 2 weeks after vaccination.
Duration of immunity: 22 weeks after vaccination.
In addition, a reduction in nasal and faecal shedding and the duration of nasal excretion of PCV2 was demonstrated in animals challenged at 4 weeks and at 22 weeks after vaccination.
Dose to be administered and administration route
For intradermal use.
Before use allow the vaccine to reach room temperature.
Shake well before use.
Administer one dose of 0.2 ml to pigs from 3 weeks of age onwards by intradermal administration at the sides of the neck using the HIPRADERMIC device.
Safety and efficacy of MHYOSPHERE PCV ID have been demonstrated using the device HIPRADERMIC.
Adverse reactions
Mild transient local reactions consisting of non-painful skin inflammations, of less than 3 cm in diameter are very common. Moderate inflammation (between 3-5 cm) at the inoculation site is commonly observed from 4 hours post-vaccination to day one.
These local reactions can be observed during the first week after vaccination and last for 1 to 4 days. One or two weeks later, these local reactions can reappear lasting for 1 to 7 days. Local reactions disappear completely within approximately 3 weeks after vaccination without treatment.
A slight transient increase in body temperature (mean 0.3 ºC, in individual pigs less than 2 ºC) occurred commonly in field studies. This slight increase subsided spontaneously within 48 hours without treatment.
Anaphylactic-type reactions (e.g. vomiting, circulatory disorders, dyspnoea) which might be life-threatening, may occur very rarely in some sensitive animals based on post-marketing safety experience. Under these circumstances, appropriate symptomatic treatment should be administered.
The frequency of adverse reactions is defined using the following convention:
- very common (more than 1 in 10 animals treated displaying adverse reactions
- common (more than 1 but less than 10 animals in 100 animals treated)
- uncommon (more than 1 but less than 10 animals in 1,000 animals treated)
- rare (more than 1 but less than 10 animals in 10,000 animals treated)
- very rare (less than 1 animal in 10,000 animals treated, including isolated reports).
