Atipam
Active substance
ATC code
Species
Cats and dogs.
Indications
Atipamezole hydrochloride is a selective α2-antagonist and is indicated for reversal of the sedative effects of medetomidine and dexmedetomidine in cats and dogs.
Dose to be administered and administration route
For single intramuscular injection in cats and dogs. Use of an appropriately graduated syringe is recommended to ensure accurate dosing when administering small volumes. Atipamezole is generally administered 15 - 60 minutes after the medetomidine or dexmedetomidine injection.
Dogs: The atipamezole hydrochloride dose (in µg) is five times that of the previous medetomidine hydrochloride dose or ten times that of the dexmedetomidine hydrochloride dose. Due to the 5-fold higher concentration of the active ingredient (atipamezole hydrochloride) in this product compared to that of preparations containing 1 mg medetomidine hydrochloride per ml and the 10-fold higher concentration compared to that of preparations containing 0.5 mg dexmedetomidine hydrochloride, an equal volume of each preparation is required.
Dosage example dogs:
| Medetomidine 1.0 mg/ml solution for injection dosage | Atipam 5.0 mg/ml solution for injection dosage |
|
0,04 ml/kg body weight (bw), i.e. 40 μg/kg bw |
0,04 ml/kg body weight (bw), i.e. 200 μg/kg bw |
| Dexmedetomidine 0.5 mg/ml solution for injection dosage | Atipam 5.0 mg/ml solution for injection dosage |
|
0,04 ml/kg body weight (bw), i.e. 20 μg/kg bw |
0,04 ml/kg body weight (bw), i.e. 200 μg/kg bw |
Cats: The atipamezole hydrochloride dose (in µg) is two-and-a-half times that of the previous medetomidine hydrochloride dose or five times that of the dexmedetomidine hydrochloride dose. Due to the 5-fold higher concentration of the active ingredient (atipamezole hydrochloride) in this product compared to that of preparations containing 1 mg medetomidine hydrochloride per ml and the 10-fold higher concentration compared to that of preparations containing 0.5 mg dexmedetomidine hydrochloride, half the volume of the product to that of the previously administered medetomidine or dexmedetomidine should be given.
Dosage example cats:
|
Medetomidine 1.0 mg/ml solution for injection dosage |
Atipam 5.0 mg/ml solution for injection dosage |
|
0,08 ml/kg body weight (bw), i.e. 80 μg/kg bw |
0,04 ml/kg body weight (bw), i.e. 200 μg/kg bw |
|
Dexmedetomidine 0.5 mg/ml solution for injection dosage |
Atipam 5.0 mg/ml solution for injection dosage |
|
0,08 ml/kg body weight (bw), i.e. 40 μg/kg bw |
0,04 ml/kg body weight (bw),, i.e. 200 μg/kg bw |
The recovery time is shortened to approximately 5 minutes. The animals become mobile after approximately 10 minutes after administration of the product.
Adverse reactions
A transient hypotensive effect has been observed during the first 10 minutes postinjection of atipamezole hydrochloride. In rare cases hyperactivity, tachycardia, salivation, atypical vocalisation, muscle tremor, vomiting, increased respiratory rate, uncontrolled urination and uncontrolled defecation may occur. In very rare cases recurrence of sedation may occur or the recovery time may not be shortened after administration of atipamezole.
In cats, when using low doses to partially reverse the effects of medetomidine or dexmedetomidine, the possibility of hypothermia (even when aroused from sedation) should be guarded against.
| PRICE | Only for registered vets. Create a free profile to access all features.. Login |
|---|---|
| Art. Nr. | 16849/4011 |
| EAN | 8714225151776 |
Similar products
Showing 4 of 4 results
Atipam
Atipam
Atipam
