Hyogen

1 x 25 dose

Emulsion for Injection

Active substance

Mycoplasma hyopneumoniae (strain 2940) (attenuated)

ATC code

QI09AB13 Mycoplasma

QI09AB Inactivated bacterial vaccines (including Mycoplasma, Toxoid and Chlamydia)

QI09A Immunologicals for pig

QI09 Immunologicals for suidae

QI Immunologicals

Species

Pigs for fattening

Indications

For the active immunisation of fattening pigs from 3 weeks of age to reduce the occurrence and severity of lung lesions caused by Mycoplasma hyopneumoniae infection.

Onset of immunity: 3 weeks

Duration of immunity: 26 weeks

Dose to be administered and administration route

Shake well before use.

Use sterile syringe and needle, respect aseptic conditions of vaccination.

When Hyogen is used alone:

Intramuscular use.

Vaccinate pigs in the side of their neck.

Administer a single dose of 2 ml from 3 weeks of age.

When Hyogen is mixed with Circovac:

The mixed use is restricted to the 100 doses (200 ml) presentations of Hyogen and to the 100 doses presentations (50 ml of reconstituted vaccine) of Circovac.

Piglets from 3 weeks of age:

Hyogen	Circovac
100 doses (200 ml of vaccine) in 250 ml bottle	100 doses for piglets (50 ml of reconstituted suspension + emulsion)

Vaccine devices should be used under aseptic conditions and in accordance with the device instructions provided by the manufacturer.

Prepare Circovac by vigorously shaking the vial of antigen suspension and injecting its content into the vial of emulsion containing adjuvant. Mix 200 ml of Hyogen and 50 ml of Circovac and shake gently until a homogeneous white emulsion is obtained.

Administer one 2.5 ml dose of the mixture by intramuscular injection, in the side of the neck.

Use the entire vaccine mixture immediately after mixing.

Adverse reactions

Target species:

Pigs for fattening

Very common

(>1 animal / 10 animals treated):

Elevated temperature*

Injection site swelling**

Uncommon

(1 to 10 animals / 1,000 animals treated):

Hypersensitivity reaction***

Vomiting***

Very rare

(<1 animal / 10,000 animals treated, including isolated reports):

Anaphylactic shock****

Recumbency****

*On the day of vaccination a transient mean increase in body temperature of about 1.3oC is very common. In an individual pig this increase might reach 2oC, but in all cases body temperature is back to normal the next day.

** A local reaction at the site of injection in the form of a swelling of a diameter up to 5 cm can be very common, which can last for three days. These reactions are of transient nature and do not need further treatment.

*** Immediate mild hypersensitivity-like reactions may occur uncommonly after vaccination, resulting in transient clinical signs such as vomiting.

**** Serious anaphylactic-type reactions (shock, recumbency) which may be fatal have been reported very rarely. Such reactions require prompt symptomatic treatment.

Reporting adverse events is important. It allows continuous safety monitoring of a veterinary medicinal product. Reports should be sent, preferably via a veterinarian, to either the marketing authorisation holder or its local representative or the national competent authority via the national reporting system. See also the last section of the package leaflet for respective contact details.