Amodip (5 - 10 kg)
Active substance
ATC code
Species
Cats
Indications
For the treatment of systemic hypertension in cats.
Dose to be administered and administration route
Oral use
Amlodipine tablets should be administered orally at a recommended starting dose of 0.125 - 0.25 mg/kg/day.
After 14 days of treatment, the dose may subsequently be doubled or increased up to 0.5 mg/kg once daily if adequate clinical response has not been achieved (e.g. systolic blood pressure remaining over 150 mmHg or a decrease of less than 15 % from the pre-treatment measurement).
|
Weight of cat (kg) |
Starting dose (number of tablets) |
|
2.5 - 5.0 |
0.5 |
|
5.1 - 10.0 |
1 |
|
10.1 and above |
2 |
The tablets can be given directly to the animals or administered with a small quantity of food.
Adverse reactions
Mild and transient emesis was a very common adverse event in the clinical trial (13%). Common adverse events were mild and transient digestive tract disorders (e.g. anorexia or diarrhoea), lethargy and dehydration.
At the dose of 0.25 mg/kg, mild hyperplastic gingivitis with some enlargement of submandibular lymph nodes has been observed very commonly in healthy young adult catsin clinical trials and very rarely in elderly cats based on the post-marketing experience. This does not usually require stopping the treatment.
The frequency of adverse reactions is defined using the following convention:
- very common (more than 1 in 10 animals treated displaying adverse reaction(s))
- common (more than 1 but less than 10 animals in 100 animals treated)
- uncommon (more than 1 but less than 10 animals in 1,000 animals treated)
- rare (more than 1 but less than 10 animals in 10,000 animals treated)
- very rare (less than 1 animal in 10,000 animals treated, including isolated reports).
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|---|---|
| Art. Nr. | 15052/4141 |
| EAN | 3411112273416 |
