Amodip (5 - 10 kg)

10 x 10 pc

Chewable tablet

Active substance

Amlodipine (Amlodipine besilate) : 1,25 mg

ATC code

QC08CA01 Amlodipine

QC08CA Dihydropyridine derivatives

QC08C Selective calcium channel blockers with mainly vascular effects

QC08 Calcium channel blockers

QC Cardiovascular system

Species

Cats

Indications

For the treatment of systemic hypertension in cats.

Dose to be administered and administration route

Oral use

Amlodipine tablets should be administered orally at a recommended starting dose of 0.125 - 0.25 mg/kg/day.

After 14 days of treatment, the dose may subsequently be doubled or increased up to 0.5 mg/kg once daily if adequate clinical response has not been achieved (e.g. systolic blood pressure remaining over 150 mmHg or a decrease of less than 15 % from the pre-treatment measurement).

Weight of cat (kg)	Starting dose (number of tablets)
2.5 - 5.0	0.5
5.1 - 10.0	1
10.1 and above	2

The tablets can be given directly to the animals or administered with a small quantity of food.

Adverse reactions

Cats:

Very common

(>1 animal / 10 animals treated):

Emesis¹, Gingival hyperplasia²

Enlarged lymph node (localised) ^2,3

Common

(1 to 10 animals / 100 animals treated):

Diarrhoea¹

Lethargy, Dehydration, Anorexia¹

¹Mild and transient

²At the dose of 0.25 mg/kg, observed in healthy young adult cats but not in the clinical trial with older hypertensive cats. This does not usually require stopping the treatment.

³Submandibular

Reporting adverse events is important. It allows continuous safety monitoring of a veterinary medicinal product. Reports should be sent, preferably via a veterinarian, to either the marketing authorisation holder or its local representative or the national competent authority via the national reporting system. See the package leaflet for respective contact details.