Semintra
Active substance
ATC code
Species
Cats
Indications
Reduction of proteinuria associated with chronic kidney disease (CKD) in cats. Treatment of systemic hypertension in cats
Dose to be administered and administration route
Oral use.
The product is to be administered once daily directly into the mouth or with a small amount of food.
The veterinary medicinal product is an oral solution and is well accepted by most cats.
The solution should be given using the measuring syringe provided in the package. The syringe fits onto the bottle and has a ml scale.
After administration of the veterinary medicinal product, close the bottle tightly with the cap, wash the measuring syringe with water and let it dry.
To avoid contamination, use the provided syringe only to administer the veterinary medicinal product.
CKD – amounts to be administered once daily:
The recommended dose is 1 mg telmisartan/kg body weight.
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Dosing: 1 mg telmisartan/kg body weight |
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|
Strength [mg/ml] |
Dosage/kg bodyweight [ml] |
|
10 |
0.1 |
Systemic hypertension – amounts to be administered once daily:
The initial recommended dose is 2 mg telmisartan/kg body weight.
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Dosing: 2 mg telmisartan/kg body weight |
||
|
Strength [mg/ml] |
Dosage/kg bodyweight [ml] |
|
|
10 |
0.2 |
|
After 4 weeks, the dosage of telmisartan may be reduced in cats with systolic blood pressure (SBP) of less than 140 mmHg (in 0.5 mg/kg increments) at the discretion of the veterinarian.
If the SBP increases over the course of the disease the daily dose may be increased again up to 2 mg/kg.
The target SBP range is between 120 and 140 mmHg. If SBP is below the target or if there are concurrent signs of hypotension, please refer to section 4.5.
Systemic hypertension associated with CKD – amounts to be administered once daily:
The dosing regimen for hypertensive cats with concomitant chronic kidney disease is as described above for systemic hypertension except that for these cats the recommended minimum effective dose is 1 mg/kg.
Adverse reactions
Cats:
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Rare (1 to 10 animals / 10,000 animals treated): |
Gastrointestinal signs (regurgitation1, vomiting2 diarrhoea2). Elevated renal parameters (creatinine and/or blood urea nitrogen), chronic renal failure. |
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Very rare (<1 animal / 10,000 |
Elevated liver enzymes3 Decreased red blood cell counts (see section 4.5). |
1 Mild and intermittent
2 Vomiting and diarrhoea are commonly reported when given at the initial treatment dose of 2 mg/kg for systemic hypertension. Mild and transient
3 Values normalised within a few days following cessation of therapy.
Reporting adverse events is important. It allows continuous safety monitoring of a veterinary medicinal product. Reports should be sent, preferably via a veterinarian, to either the marketing authorisation holder or its local representative or the national competent authority via the national reporting system. See also the last section of the package leaflet for respective contact details.
| PRICE | Only for registered vets. Create a free profile to access all features.. Login |
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| Art. Nr. | 04491/5058 |
| EAN | 5012917030204 |
